Therasabdab Tools¶

Configuration File: therasabdab_tools.json Tool Type: Local Tools Count: 3

This page contains all tools defined in the therasabdab_tools.json configuration file.

Available Tools¶

TheraSAbDab_get_all_therapeutics (Type: TheraSAbDabTool)¶

Get summary of all therapeutic antibodies in Thera-SAbDab database. Returns counts by format (IgG


TheraSAbDab_get_all_therapeutics tool specification

Tool Information:

  • Name: TheraSAbDab_get_all_therapeutics

  • Type: TheraSAbDabTool

  • Description: Get summary of all therapeutic antibodies in Thera-SAbDab database. Returns counts by format (IgG, bispecific, ADC) and clinical phase. Use for landscape analysis of antibody therapeutics.

Parameters:

No parameters required.

Example Usage:

query = {
    "name": "TheraSAbDab_get_all_therapeutics",
    "arguments": {
    }
}
result = tu.run(query)

TheraSAbDab_search_by_target (Type: TheraSAbDabTool)¶

Find therapeutic antibodies targeting a specific antigen. Returns all clinical/approved antibodie


TheraSAbDab_search_by_target tool specification

Tool Information:

  • Name: TheraSAbDab_search_by_target

  • Type: TheraSAbDabTool

  • Description: Find therapeutic antibodies targeting a specific antigen. Returns all clinical/approved antibodies against the target (e.g., all anti-PD1 antibodies). Essential for competitive landscape analysis.

Parameters:

  • target (string) (required) Target antigen name (e.g., ‘PD-1’, ‘HER2’, ‘CD20’, ‘TNF-alpha’, ‘VEGF’)

Example Usage:

query = {
    "name": "TheraSAbDab_search_by_target",
    "arguments": {
        "target": "example_value"
    }
}
result = tu.run(query)

TheraSAbDab_search_therapeutics (Type: TheraSAbDabTool)¶

Search therapeutic antibodies by name in Thera-SAbDab. Returns WHO INN name, target antigen, form


TheraSAbDab_search_therapeutics tool specification

Tool Information:

  • Name: TheraSAbDab_search_therapeutics

  • Type: TheraSAbDabTool

  • Description: Search therapeutic antibodies by name in Thera-SAbDab. Returns WHO INN name, target antigen, format (IgG, bispecific, ADC), clinical phase, and PDB structures. Use for finding approved/clinical antibody drugs.

Parameters:

  • query (string) (required) Search query - antibody name (e.g., ‘trastuzumab’, ‘pembrolizumab’, ‘rituximab’)

Example Usage:

query = {
    "name": "TheraSAbDab_search_therapeutics",
    "arguments": {
        "query": "example_value"
    }
}
result = tu.run(query)