Ebi Proteins Epitope Tools

Configuration File: ebi_proteins_epitope_tools.json Tool Type: Local Tools Count: 1

This page contains all tools defined in the ebi_proteins_epitope_tools.json configuration file.

Available Tools

EBIProteins_get_epitopes (Type: EBIProteinsEpitopeTool)

Get experimentally-determined immune epitope regions for a protein using the EBI Proteins API. Re…

EBIProteins_get_epitopes tool specification

Tool Information:

  • Name: EBIProteins_get_epitopes

  • Type: EBIProteinsEpitopeTool

  • Description: Get experimentally-determined immune epitope regions for a protein using the EBI Proteins API. Returns epitope positions, sequences, and supporting literature from the Immune Epitope Database (IEDB). Epitopes are regions of proteins recognized by antibodies or T-cells. Critical for vaccine design, therapeutic antibody development, immunogenicity assessment, and understanding immune responses. Example: get epitopes for P04637 (TP53) returns 62 experimentally-mapped epitope regions; P00533 (EGFR) returns epitopes relevant to cancer immunotherapy.

Parameters:

  • accession (string) (required) UniProt accession number for the protein. Examples: ‘P04637’ (TP53), ‘P00533’ (EGFR), ‘P01308’ (insulin), ‘P0DTC2’ (SARS-CoV-2 spike protein).

Example Usage:

query = {
    "name": "EBIProteins_get_epitopes",
    "arguments": {
        "accession": "example_value"
    }
}
result = tu.run(query)