Iupred3 Tools

Configuration File: iupred3_tools.json Tool Type: Local Tools Count: 1

This page contains all tools defined in the iupred3_tools.json configuration file.

Available Tools

IUPred3_predict_disorder (Type: IUPred3Tool)

Predict intrinsically disordered protein regions from sequence using the IUPred3 algorithm. Input…

IUPred3_predict_disorder tool specification

Tool Information:

  • Name: IUPred3_predict_disorder

  • Type: IUPred3Tool

  • Description: Predict intrinsically disordered protein regions from sequence using the IUPred3 algorithm. Input a UniProt accession or ID (e.g. P04637 for human p53). Returns per-residue disorder scores (0-1, higher = more disordered), predicted disordered region segments (score >= 0.5), and summary statistics. The ‘anchor’ type additionally returns ANCHOR2 protein-binding region scores; ‘redox’ returns redox-state-dependent disorder. Unlike MobiDB/DisProt (database lookups), this runs the IUPred prediction on demand. No authentication required. Note: IUPred3 is free for academic/non-commercial use; commercial use requires a license from the authors.

Parameters:

  • accession (string) (required) UniProt accession or entry ID, e.g. ‘P04637’ (human p53) or ‘TP53_HUMAN’. The IUPred3 server links to the latest UniProt release and fetches the sequence automatically.

  • iupred_type (string) (optional) Prediction mode. ‘long’ (default) = long disordered regions; ‘short’ = short disorder (e.g. missing PDB residues); ‘anchor’ = long disorder plus ANCHOR2 binding-region scores; ‘glob’ = globular-domain-aware disorder; ‘redox’ = redox-state-dependent disorder.

Example Usage:

query = {
    "name": "IUPred3_predict_disorder",
    "arguments": {
        "accession": "example_value"
    }
}
result = tu.run(query)