Opentarget Tools

Configuration File: opentarget_tools.json Tool Type: Local Tools Count: 53

This page contains all tools defined in the opentarget_tools.json configuration file.

Available Tools

OpenTargets_drug_pharmacogenomics_data (Type: OpenTarget)

Retrieve pharmacogenomics data for a specific drug, including evidence levels and genotype annota…

OpenTargets_drug_pharmacogenomics_data tool specification

Tool Information:

• Name: OpenTargets_drug_pharmacogenomics_data

• Type: OpenTarget

• Description: Retrieve pharmacogenomics data for a specific drug, including evidence levels and genotype annotations.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

• page (object) (optional) Pagination options.

Example Usage:

query = {
    "name": "OpenTargets_drug_pharmacogenomics_data",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_approved_indications_by_drug_chemblId (Type: OpenTarget)

Retrieve detailed information about multiple drugs using a list of ChEMBL IDs.

OpenTargets_get_approved_indications_by_drug_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_approved_indications_by_drug_chemblId

• Type: OpenTarget

• Description: Retrieve detailed information about multiple drugs using a list of ChEMBL IDs.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_approved_indications_by_drug_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_associated_diseases_by_drug_chemblId (Type: OpenTarget)

Retrieve the list of diseases associated with a specific drug chemblId based on clinical trial da…

OpenTargets_get_associated_diseases_by_drug_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_associated_diseases_by_drug_chemblId

• Type: OpenTarget

• Description: Retrieve the list of diseases associated with a specific drug chemblId based on clinical trial data or post-marketed drugs.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_associated_diseases_by_drug_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_associated_drugs_by_disease_efoId (Type: OpenTarget)

Retrieve known drugs associated with a specific disease by disease efoId.

OpenTargets_get_associated_drugs_by_disease_efoId tool specification

Tool Information:

• Name: OpenTargets_get_associated_drugs_by_disease_efoId

• Type: OpenTarget

• Description: Retrieve known drugs associated with a specific disease by disease efoId.

Parameters:

• efoId (string) (optional) The EFO ID of the disease.

• size (integer) (optional) Number of entries to fetch, recomanding a large number to avoid missing drugs.

Example Usage:

query = {
    "name": "OpenTargets_get_associated_drugs_by_disease_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_associated_drugs_by_target_ensemblID (Type: OpenTarget)

Get known drugs and information (e.g. id, name, MoA) associated with a specific target ensemblID,…

OpenTargets_get_associated_drugs_by_target_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_associated_drugs_by_target_ensemblID

• Type: OpenTarget

• Description: Get known drugs and information (e.g. id, name, MoA) associated with a specific target ensemblID, including clinical trial phase and mechanism of action of the drugs.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target.

• size (integer) (optional) Number of entries to fetch.

• cursor (string) (optional) Cursor for pagination.

Example Usage:

query = {
    "name": "OpenTargets_get_associated_drugs_by_target_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_associated_phenotypes_by_disease_efoId (Type: OpenTarget)

Find HPO phenotypes asosciated with the specified disease efoId.

OpenTargets_get_associated_phenotypes_by_disease_efoId tool specification

Tool Information:

• Name: OpenTargets_get_associated_phenotypes_by_disease_efoId

• Type: OpenTarget

• Description: Find HPO phenotypes asosciated with the specified disease efoId.

Parameters:

• efoId (string) (optional) The efoId of a disease or phenotype.

Example Usage:

query = {
    "name": "OpenTargets_get_associated_phenotypes_by_disease_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_associated_targets_by_disease_efoId (Type: OpenTarget)

Find targets associated with a specific disease or phenotype based on efoId.

OpenTargets_get_associated_targets_by_disease_efoId tool specification

Tool Information:

• Name: OpenTargets_get_associated_targets_by_disease_efoId

• Type: OpenTarget

• Description: Find targets associated with a specific disease or phenotype based on efoId.

Parameters:

• efoId (string) (optional) The efoId of a disease or phenotype.

Example Usage:

query = {
    "name": "OpenTargets_get_associated_targets_by_disease_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_associated_targets_by_drug_chemblId (Type: OpenTarget)

Retrieve the list of targets linked to a specific drug chemblId based on its mechanism of action.

OpenTargets_get_associated_targets_by_drug_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_associated_targets_by_drug_chemblId

• Type: OpenTarget

• Description: Retrieve the list of targets linked to a specific drug chemblId based on its mechanism of action.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_associated_targets_by_drug_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_biological_mouse_models_by_ensemblID (Type: OpenTarget)

Retrieve biological mouse models, including allelic compositions and genetic backgrounds, for a s…

OpenTargets_get_biological_mouse_models_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_biological_mouse_models_by_ensemblID

• Type: OpenTarget

• Description: Retrieve biological mouse models, including allelic compositions and genetic backgrounds, for a specific target.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target.

Example Usage:

query = {
    "name": "OpenTargets_get_biological_mouse_models_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_chemical_probes_by_target_ensemblID (Type: OpenTarget)

Retrieve chemical probes associated with a specific target using its ensemblID.

OpenTargets_get_chemical_probes_by_target_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_chemical_probes_by_target_ensemblID

• Type: OpenTarget

• Description: Retrieve chemical probes associated with a specific target using its ensemblID.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target for which to retrieve chemical probes.

Example Usage:

query = {
    "name": "OpenTargets_get_chemical_probes_by_target_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_disease_ancestors_parents_by_efoId (Type: OpenTarget)

Retrieve the disease ancestors and parents in the ontology using the disease EFO ID.

OpenTargets_get_disease_ancestors_parents_by_efoId tool specification

Tool Information:

• Name: OpenTargets_get_disease_ancestors_parents_by_efoId

• Type: OpenTarget

• Description: Retrieve the disease ancestors and parents in the ontology using the disease EFO ID.

Parameters:

• efoId (string) (optional) The EFO ID of the disease.

Example Usage:

query = {
    "name": "OpenTargets_get_disease_ancestors_parents_by_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_disease_descendants_children_by_efoId (Type: OpenTarget)

Retrieve the disease descendants and children in the ontology using the disease EFO ID.

OpenTargets_get_disease_descendants_children_by_efoId tool specification

Tool Information:

• Name: OpenTargets_get_disease_descendants_children_by_efoId

• Type: OpenTarget

• Description: Retrieve the disease descendants and children in the ontology using the disease EFO ID.

Parameters:

• efoId (string) (optional) The EFO ID of the disease.

Example Usage:

query = {
    "name": "OpenTargets_get_disease_descendants_children_by_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_disease_description_by_efoId (Type: OpenTarget)

Retrieve disease description, name, database cros references, obsolete terms, and whether it’s a …

OpenTargets_get_disease_description_by_efoId tool specification

Tool Information:

• Name: OpenTargets_get_disease_description_by_efoId

• Type: OpenTarget

• Description: Retrieve disease description, name, database cros references, obsolete terms, and whether it’s a therapeutic area, all using the specified efoId.

Parameters:

• efoId (string) (optional) The EFO ID of the disease.

Example Usage:

query = {
    "name": "OpenTargets_get_disease_description_by_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_disease_id_description_by_name (Type: OpenTarget)

Retrieve the efoId and additional details of a disease based on its name.

OpenTargets_get_disease_id_description_by_name tool specification

Tool Information:

• Name: OpenTargets_get_disease_id_description_by_name

• Type: OpenTarget

• Description: Retrieve the efoId and additional details of a disease based on its name.

Parameters:

• diseaseName (string) (optional) The name of the disease to search for.

Example Usage:

query = {
    "name": "OpenTargets_get_disease_id_description_by_name",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_disease_locations_by_efoId (Type: OpenTarget)

Retrieve the disease’s direct location and indirect location disease terms and IDs using the dise…

OpenTargets_get_disease_locations_by_efoId tool specification

Tool Information:

• Name: OpenTargets_get_disease_locations_by_efoId

• Type: OpenTarget

• Description: Retrieve the disease’s direct location and indirect location disease terms and IDs using the disease EFO ID.

Parameters:

• efoId (string) (optional) The EFO ID of the disease.

Example Usage:

query = {
    "name": "OpenTargets_get_disease_locations_by_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_disease_synonyms_by_efoId (Type: OpenTarget)

Retrieve disease synonyms by its EFO ID.

OpenTargets_get_disease_synonyms_by_efoId tool specification

Tool Information:

• Name: OpenTargets_get_disease_synonyms_by_efoId

• Type: OpenTarget

• Description: Retrieve disease synonyms by its EFO ID.

Parameters:

• efoId (string) (optional) The EFO ID of the disease.

Example Usage:

query = {
    "name": "OpenTargets_get_disease_synonyms_by_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_disease_therapeutic_areas_by_efoId (Type: OpenTarget)

Retrieve the therapeutic areas associated with a specific disease efoId.

OpenTargets_get_disease_therapeutic_areas_by_efoId tool specification

Tool Information:

• Name: OpenTargets_get_disease_therapeutic_areas_by_efoId

• Type: OpenTarget

• Description: Retrieve the therapeutic areas associated with a specific disease efoId.

Parameters:

• efoId (string) (optional) The EFO ID of the disease.

Example Usage:

query = {
    "name": "OpenTargets_get_disease_therapeutic_areas_by_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_diseases_phenotypes_by_target_ensembl (Type: OpenTarget)

Find diseases or phenotypes associated with a specific target using ensemblId.

OpenTargets_get_diseases_phenotypes_by_target_ensembl tool specification

Tool Information:

• Name: OpenTargets_get_diseases_phenotypes_by_target_ensembl

• Type: OpenTarget

• Description: Find diseases or phenotypes associated with a specific target using ensemblId.

Parameters:

• ensemblId (string) (optional) The ensemblId of a target.

Example Usage:

query = {
    "name": "OpenTargets_get_diseases_phenotypes_by_target_ensembl",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_adverse_events_by_chemblId (Type: OpenTarget)

Retrieve significant adverse events reported for a specific drug chemblId.

OpenTargets_get_drug_adverse_events_by_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_drug_adverse_events_by_chemblId

• Type: OpenTarget

• Description: Retrieve significant adverse events reported for a specific drug chemblId.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

• page (object) (optional) Pagination settings.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_adverse_events_by_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_approval_status_by_chemblId (Type: OpenTarget)

Retrieve the approval status of a specific drug chemblId.

OpenTargets_get_drug_approval_status_by_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_drug_approval_status_by_chemblId

• Type: OpenTarget

• Description: Retrieve the approval status of a specific drug chemblId.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_approval_status_by_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_chembId_by_generic_name (Type: OpentargetToolDrugNameMatch)

Fetch the drug chemblId and description based on the drug generic name.

OpenTargets_get_drug_chembId_by_generic_name tool specification

Tool Information:

• Name: OpenTargets_get_drug_chembId_by_generic_name

• Type: OpentargetToolDrugNameMatch

• Description: Fetch the drug chemblId and description based on the drug generic name.

Parameters:

• drugName (string) (optional) The generic name of the drug for which the ID is required.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_chembId_by_generic_name",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_description_by_chemblId (Type: OpenTarget)

Get drug name, year of first approval, type, cross references, and max clinical trial phase based…

OpenTargets_get_drug_description_by_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_drug_description_by_chemblId

• Type: OpenTarget

• Description: Get drug name, year of first approval, type, cross references, and max clinical trial phase based on specified chemblId.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_description_by_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_id_description_by_name (Type: OpentargetToolDrugNameMatch)

Fetch the drug chemblId and description based on the drug generic name.

OpenTargets_get_drug_id_description_by_name tool specification

Tool Information:

• Name: OpenTargets_get_drug_id_description_by_name

• Type: OpentargetToolDrugNameMatch

• Description: Fetch the drug chemblId and description based on the drug generic name.

Parameters:

• drugName (string) (optional) The name of the drug for which the ID is required.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_id_description_by_name",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_indications_by_chemblId (Type: OpenTarget)

Fetch indications (treatable phenotypes/diseases) for a given drug chemblId.

OpenTargets_get_drug_indications_by_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_drug_indications_by_chemblId

• Type: OpenTarget

• Description: Fetch indications (treatable phenotypes/diseases) for a given drug chemblId.

Parameters:

• chemblId (string) (optional) The chemblId of the drug for which to retrieve treatable phenotypes information.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_indications_by_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_mechanisms_of_action_by_chemblId (Type: OpenTarget)

Retrieve the mechanisms of action associated with a specific drug using chemblId.

OpenTargets_get_drug_mechanisms_of_action_by_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_drug_mechanisms_of_action_by_chemblId

• Type: OpenTarget

• Description: Retrieve the mechanisms of action associated with a specific drug using chemblId.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_mechanisms_of_action_by_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_synonyms_by_chemblId (Type: OpenTarget)

Retrieve the synonyms associated with a specific drug chemblId.

OpenTargets_get_drug_synonyms_by_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_drug_synonyms_by_chemblId

• Type: OpenTarget

• Description: Retrieve the synonyms associated with a specific drug chemblId.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_synonyms_by_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_trade_names_by_chemblId (Type: OpenTarget)

Retrieve the trade names associated with a specific drug chemblId.

OpenTargets_get_drug_trade_names_by_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_drug_trade_names_by_chemblId

• Type: OpenTarget

• Description: Retrieve the trade names associated with a specific drug chemblId.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_trade_names_by_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_warnings_by_chemblId (Type: OpenTarget)

Retrieve warnings for a specific drug using ChEMBL ID.

OpenTargets_get_drug_warnings_by_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_drug_warnings_by_chemblId

• Type: OpenTarget

• Description: Retrieve warnings for a specific drug using ChEMBL ID.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_warnings_by_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_drug_withdrawn_blackbox_status_by_chemblId (Type: OpenTarget)

Find withdrawn and black-box warning statuses for a specific drug by chemblId.

OpenTargets_get_drug_withdrawn_blackbox_status_by_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_drug_withdrawn_blackbox_status_by_chemblId

• Type: OpenTarget

• Description: Find withdrawn and black-box warning statuses for a specific drug by chemblId.

Parameters:

• chemblId (array) (optional) The chemblId of a drug.

Example Usage:

query = {
    "name": "OpenTargets_get_drug_withdrawn_blackbox_status_by_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_gene_ontology_terms_by_goID (Type: OpenTarget)

Retrieve Gene Ontology terms based on a list of GO IDs.

OpenTargets_get_gene_ontology_terms_by_goID tool specification

Tool Information:

• Name: OpenTargets_get_gene_ontology_terms_by_goID

• Type: OpenTarget

• Description: Retrieve Gene Ontology terms based on a list of GO IDs.

Parameters:

• goIds (array) (optional) A list of Gene Ontology (GO) IDs to fetch the corresponding terms.

Example Usage:

query = {
    "name": "OpenTargets_get_gene_ontology_terms_by_goID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_known_drugs_by_drug_chemblId (Type: OpenTarget)

Get a list of known drugs and associated information using the specified chemblId.

OpenTargets_get_known_drugs_by_drug_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_known_drugs_by_drug_chemblId

• Type: OpenTarget

• Description: Get a list of known drugs and associated information using the specified chemblId.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_known_drugs_by_drug_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_parent_child_molecules_by_drug_chembl_ID (Type: OpenTarget)

Get parent and child molecules of specified drug chemblId.

OpenTargets_get_parent_child_molecules_by_drug_chembl_ID tool specification

Tool Information:

• Name: OpenTargets_get_parent_child_molecules_by_drug_chembl_ID

• Type: OpenTarget

• Description: Get parent and child molecules of specified drug chemblId.

Parameters:

• chemblId (string) (optional) The ChEMBL ID of the drug.

Example Usage:

query = {
    "name": "OpenTargets_get_parent_child_molecules_by_drug_chembl_ID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_publications_by_disease_efoId (Type: OpenTarget)

Retrieve publications related to a disease efoId, including PubMed IDs and publication dates.

OpenTargets_get_publications_by_disease_efoId tool specification

Tool Information:

• Name: OpenTargets_get_publications_by_disease_efoId

• Type: OpenTarget

• Description: Retrieve publications related to a disease efoId, including PubMed IDs and publication dates.

Parameters:

• entityId (string) (optional) The ID of the entity (efoId).

• additionalIds (array) (optional) List of additional IDs to include in the search.

• startYear (integer) (optional) Year at the lower end of the filter.

• startMonth (integer) (optional) Month at the lower end of the filter.

• endYear (integer) (optional) Year at the higher end of the filter.

• endMonth (integer) (optional) Month at the higher end of the filter.

Example Usage:

query = {
    "name": "OpenTargets_get_publications_by_disease_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_publications_by_drug_chemblId (Type: OpenTarget)

Retrieve publications related to a drug chemblId, including PubMed IDs and publication dates.

OpenTargets_get_publications_by_drug_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_publications_by_drug_chemblId

• Type: OpenTarget

• Description: Retrieve publications related to a drug chemblId, including PubMed IDs and publication dates.

Parameters:

• entityId (string) (optional) The ID of the entity (chemblId).

• additionalIds (array) (optional) List of additional IDs to include in the search.

• startYear (integer) (optional) Year at the lower end of the filter.

• startMonth (integer) (optional) Month at the lower end of the filter.

• endYear (integer) (optional) Year at the higher end of the filter.

• endMonth (integer) (optional) Month at the higher end of the filter.

Example Usage:

query = {
    "name": "OpenTargets_get_publications_by_drug_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_publications_by_target_ensemblID (Type: OpenTarget)

Retrieve publications related to a target ensemblID, including PubMed IDs and publication dates.

OpenTargets_get_publications_by_target_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_publications_by_target_ensemblID

• Type: OpenTarget

• Description: Retrieve publications related to a target ensemblID, including PubMed IDs and publication dates.

Parameters:

• entityId (string) (optional) The ID of the entity (ensemblID).

• additionalIds (array) (optional) List of additional IDs to include in the search.

• startYear (integer) (optional) Year at the lower end of the filter.

• startMonth (integer) (optional) Month at the lower end of the filter.

• endYear (integer) (optional) Year at the higher end of the filter.

• endMonth (integer) (optional) Month at the higher end of the filter.

Example Usage:

query = {
    "name": "OpenTargets_get_publications_by_target_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_similar_entities_by_disease_efoId (Type: OpenTarget)

Retrieve similar entities for a given disease efoId using a model trained with PubMed.

OpenTargets_get_similar_entities_by_disease_efoId tool specification

Tool Information:

• Name: OpenTargets_get_similar_entities_by_disease_efoId

• Type: OpenTarget

• Description: Retrieve similar entities for a given disease efoId using a model trained with PubMed.

Parameters:

• efoId (string) (optional) The EFO ID of the disease.

• threshold (number) (optional) Threshold similarity between 0 and 1. Only results above threshold are returned.

• size (integer) (optional) Number of similar entities to fetch.

Example Usage:

query = {
    "name": "OpenTargets_get_similar_entities_by_disease_efoId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_similar_entities_by_drug_chemblId (Type: OpenTarget)

Retrieve similar entities for a given drug chemblId using a model trained with PubMed.

OpenTargets_get_similar_entities_by_drug_chemblId tool specification

Tool Information:

• Name: OpenTargets_get_similar_entities_by_drug_chemblId

• Type: OpenTarget

• Description: Retrieve similar entities for a given drug chemblId using a model trained with PubMed.

Parameters:

• chemblId (string) (optional) The chemblId of the disease.

• threshold (number) (optional) Threshold similarity between 0 and 1. Only results above threshold are returned.

• size (integer) (optional) Number of similar entities to fetch.

Example Usage:

query = {
    "name": "OpenTargets_get_similar_entities_by_drug_chemblId",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_similar_entities_by_target_ensemblID (Type: OpenTarget)

Retrieve similar entities for a given target ensemblID using a model trained with PubMed.

OpenTargets_get_similar_entities_by_target_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_similar_entities_by_target_ensemblID

• Type: OpenTarget

• Description: Retrieve similar entities for a given target ensemblID using a model trained with PubMed.

Parameters:

• ensemblId (string) (optional) The ensemblID of the disease.

• threshold (number) (optional) Threshold similarity between 0 and 1. Only results above threshold are returned.

• size (integer) (optional) Number of similar entities to fetch.

Example Usage:

query = {
    "name": "OpenTargets_get_similar_entities_by_target_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_classes_by_ensemblID (Type: OpenTarget)

Retrieve the target classes associated with a specific target ensemblID.

OpenTargets_get_target_classes_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_classes_by_ensemblID

• Type: OpenTarget

• Description: Retrieve the target classes associated with a specific target ensemblID.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target.

Example Usage:

query = {
    "name": "OpenTargets_get_target_classes_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_constraint_info_by_ensemblID (Type: OpenTarget)

Retrieve genetic constraint information for a specific target ensemblID, including expected and o…

OpenTargets_get_target_constraint_info_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_constraint_info_by_ensemblID

• Type: OpenTarget

• Description: Retrieve genetic constraint information for a specific target ensemblID, including expected and observed values, and scores.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target.

Example Usage:

query = {
    "name": "OpenTargets_get_target_constraint_info_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_enabling_packages_by_ensemblID (Type: OpenTarget)

Retrieve the Target Enabling Packages (TEP) associated with a specific target ensemblID.

OpenTargets_get_target_enabling_packages_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_enabling_packages_by_ensemblID

• Type: OpenTarget

• Description: Retrieve the Target Enabling Packages (TEP) associated with a specific target ensemblID.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target.

Example Usage:

query = {
    "name": "OpenTargets_get_target_enabling_packages_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_gene_ontology_by_ensemblID (Type: OpenTarget)

Retrieve Gene Ontology annotations for a specific target by Ensembl ID.

OpenTargets_get_target_gene_ontology_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_gene_ontology_by_ensemblID

• Type: OpenTarget

• Description: Retrieve Gene Ontology annotations for a specific target by Ensembl ID.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target for which to retrieve Gene Ontology annotations.

Example Usage:

query = {
    "name": "OpenTargets_get_target_gene_ontology_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_genomic_location_by_ensemblID (Type: OpenTarget)

Retrieve genomic location data for a specific target, including chromosome, start, end, and strand.

OpenTargets_get_target_genomic_location_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_genomic_location_by_ensemblID

• Type: OpenTarget

• Description: Retrieve genomic location data for a specific target, including chromosome, start, end, and strand.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target for which to retrieve genomic location information.

Example Usage:

query = {
    "name": "OpenTargets_get_target_genomic_location_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_homologues_by_ensemblID (Type: OpenTarget)

Fetch homologues for a specific target by Ensembl ID.

OpenTargets_get_target_homologues_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_homologues_by_ensemblID

• Type: OpenTarget

• Description: Fetch homologues for a specific target by Ensembl ID.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target for which to retrieve homologues.

Example Usage:

query = {
    "name": "OpenTargets_get_target_homologues_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_id_description_by_name (Type: OpenTarget)

Get the ensemblId and description based on the target name.

OpenTargets_get_target_id_description_by_name tool specification

Tool Information:

• Name: OpenTargets_get_target_id_description_by_name

• Type: OpenTarget

• Description: Get the ensemblId and description based on the target name.

Parameters:

• targetName (string) (optional) The name of the target for which the ID is required.

Example Usage:

query = {
    "name": "OpenTargets_get_target_id_description_by_name",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_interactions_by_ensemblID (Type: OpenTarget)

Retrieve interaction data for a specific target ensemblID, including interaction partners and evi…

OpenTargets_get_target_interactions_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_interactions_by_ensemblID

• Type: OpenTarget

• Description: Retrieve interaction data for a specific target ensemblID, including interaction partners and evidence.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target.

• page (object) (optional) Pagination parameters.

Example Usage:

query = {
    "name": "OpenTargets_get_target_interactions_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_safety_profile_by_ensemblID (Type: OpenTarget)

Retrieve known target safety liabilities for a specific target Ensembl ID.

OpenTargets_get_target_safety_profile_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_safety_profile_by_ensemblID

• Type: OpenTarget

• Description: Retrieve known target safety liabilities for a specific target Ensembl ID.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target for which to retrieve safety liabilities.

Example Usage:

query = {
    "name": "OpenTargets_get_target_safety_profile_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_subcellular_locations_by_ensemblID (Type: OpenTarget)

Retrieve information about subcellular locations for a specific target ensemblID.

OpenTargets_get_target_subcellular_locations_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_subcellular_locations_by_ensemblID

• Type: OpenTarget

• Description: Retrieve information about subcellular locations for a specific target ensemblID.

Parameters:

• ensemblId (string) (optional) The ensemblId of a target.

Example Usage:

query = {
    "name": "OpenTargets_get_target_subcellular_locations_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_synonyms_by_ensemblID (Type: OpenTarget)

Retrieve synonyms for specified target, including alternative names and symbols, using given ense…

OpenTargets_get_target_synonyms_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_synonyms_by_ensemblID

• Type: OpenTarget

• Description: Retrieve synonyms for specified target, including alternative names and symbols, using given ensemblID.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target.

Example Usage:

query = {
    "name": "OpenTargets_get_target_synonyms_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_get_target_tractability_by_ensemblID (Type: OpenTarget)

Retrieve tractability assessments, including modality and values, for a specific target ensembl ID.

OpenTargets_get_target_tractability_by_ensemblID tool specification

Tool Information:

• Name: OpenTargets_get_target_tractability_by_ensemblID

• Type: OpenTarget

• Description: Retrieve tractability assessments, including modality and values, for a specific target ensembl ID.

Parameters:

• ensemblId (string) (optional) The Ensembl ID of the target.

Example Usage:

query = {
    "name": "OpenTargets_get_target_tractability_by_ensemblID",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_multi_entity_search_by_query_string (Type: OpenTarget)

Perform a multi-entity search based on a query string, filtering by entity names and pagination s…

OpenTargets_multi_entity_search_by_query_string tool specification

Tool Information:

• Name: OpenTargets_multi_entity_search_by_query_string

• Type: OpenTarget

• Description: Perform a multi-entity search based on a query string, filtering by entity names and pagination settings.

Parameters:

• queryString (string) (optional) The search string for querying information.

• entityNames (array) (optional) List of entity names to search for (e.g., target, disease, drug).

• page (object) (optional) Pagination settings with index and size.

Example Usage:

query = {
    "name": "OpenTargets_multi_entity_search_by_query_string",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_search_category_counts_by_query_string (Type: OpenTarget)

Get the count of entries in each entity category (disease, target, drug) based on a query string.

OpenTargets_search_category_counts_by_query_string tool specification

Tool Information:

• Name: OpenTargets_search_category_counts_by_query_string

• Type: OpenTarget

• Description: Get the count of entries in each entity category (disease, target, drug) based on a query string.

Parameters:

• queryString (string) (optional) The search string for querying information.

Example Usage:

query = {
    "name": "OpenTargets_search_category_counts_by_query_string",
    "arguments": {
    }
}
result = tu.run(query)

OpenTargets_target_disease_evidence (Type: OpenTarget)

Explore evidence that supports a specific target-disease association. Input is disease efoId and …

OpenTargets_target_disease_evidence tool specification

Tool Information:

• Name: OpenTargets_target_disease_evidence

• Type: OpenTarget

• Description: Explore evidence that supports a specific target-disease association. Input is disease efoId and target ensemblID.

Parameters:

• efoId (string) (optional) The efoId of a disease or phenotype.

• ensemblId (string) (optional) The ensemblId of a target.

Example Usage:

query = {
    "name": "OpenTargets_target_disease_evidence",
    "arguments": {
    }
}
result = tu.run(query)

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