Iedb Ext Tools

Configuration File: iedb_ext_tools.json Tool Type: Local Tools Count: 4

This page contains all tools defined in the iedb_ext_tools.json configuration file.

Available Tools

iedb_get_epitope_tcell_assays (Type: IEDBTool)

Get T-cell assay data linked to a specific epitope structure ID. Given an epitope_id (from iedb_s…

iedb_get_epitope_tcell_assays tool specification

Tool Information:

  • Name: iedb_get_epitope_tcell_assays

  • Type: IEDBTool

  • Description: Get T-cell assay data linked to a specific epitope structure ID. Given an epitope_id (from iedb_search_epitopes), returns all T-cell assays that tested this epitope.

Useful for understanding the T-cell immunogenicity of a known epitope.

Parameters:

  • epitope_id (integer) (required) IEDB epitope structure ID (from iedb_search_epitopes results). Example: 20354 for GILGFVFTL.

  • limit (integer) (optional) Maximum rows to return.

  • offset (integer) (optional) Pagination offset.

  • select (unknown) (optional) Columns to return.

  • filters (object) (optional) Additional PostgREST filters.

Example Usage:

query = {
    "name": "iedb_get_epitope_tcell_assays",
    "arguments": {
        "epitope_id": 10
    }
}
result = tu.run(query)

iedb_search_bcr_sequences (Type: IEDBTool)

Search B-cell receptor (BCR) / antibody sequence data from the IEDB. Returns antibody sequences w…

iedb_search_bcr_sequences tool specification

Tool Information:

  • Name: iedb_search_bcr_sequences

  • Type: IEDBTool

  • Description: Search B-cell receptor (BCR) / antibody sequence data from the IEDB. Returns antibody sequences with heavy/light chain CDR3 sequences and cognate epitope information.

Useful for antibody discovery, therapeutic antibody engineering, and studying humoral immune responses.

Parameters:

  • limit (integer) (optional) Maximum rows to return.

  • offset (integer) (optional) Pagination offset.

  • select (unknown) (optional) Columns to return.

  • filters (object) (optional) PostgREST filters. Key columns: receptor_group_id, receptor_type, receptor_name, chain_type, v_gene, j_gene.

Example Usage:

query = {
    "name": "iedb_search_bcr_sequences",
    "arguments": {
    }
}
result = tu.run(query)

iedb_search_tcell_assays (Type: IEDBTool)

Search T-cell assay data from the IEDB. Returns T-cell response assays with epitope sequences, MH…

iedb_search_tcell_assays tool specification

Tool Information:

  • Name: iedb_search_tcell_assays

  • Type: IEDBTool

  • Description: Search T-cell assay data from the IEDB. Returns T-cell response assays with epitope sequences, MHC restriction, source organism, and assay results.

Useful for finding T-cell epitopes for vaccine design, immunotherapy, and understanding cellular immunity. Filter by peptide sequence, MHC class, organism, or qualitative result.

Tip: use select to request only key fields for faster responses.

Parameters:

  • sequence (string) (optional) Exact peptide sequence to search (e.g., GILGFVFTL for influenza M1 epitope).

  • sequence_contains (string) (optional) Partial peptide sequence (substring match). Example: ‘SIINFEKL’.

  • mhc_class (string) (optional) MHC class restriction (I or II).

  • qualitative_measure (string) (optional) Filter by assay result.

  • limit (integer) (optional) Maximum rows to return.

  • offset (integer) (optional) Pagination offset.

  • select (unknown) (optional) Columns to return (array of strings). Example: [‘tcell_id’,’linear_sequence’,’mhc_restriction’,’qualitative_measure’].

  • filters (object) (optional) Advanced PostgREST filters (e.g., {“source_organism_iri”:”eq.NCBITaxon:11320”}).

Example Usage:

query = {
    "name": "iedb_search_tcell_assays",
    "arguments": {
    }
}
result = tu.run(query)

iedb_search_tcr_sequences (Type: IEDBTool)

Search T-cell receptor (TCR) sequence data from the IEDB. Returns TCR sequences paired with their…

iedb_search_tcr_sequences tool specification

Tool Information:

  • Name: iedb_search_tcr_sequences

  • Type: IEDBTool

  • Description: Search T-cell receptor (TCR) sequence data from the IEDB. Returns TCR sequences paired with their cognate epitopes and MHC restriction.

Useful for TCR engineering, adoptive cell therapy design, and understanding antigen-specific T-cell responses.

Parameters:

  • limit (integer) (optional) Maximum rows to return.

  • offset (integer) (optional) Pagination offset.

  • select (unknown) (optional) Columns to return.

  • filters (object) (optional) PostgREST filters. Key columns: receptor_group_id, receptor_type, receptor_name, cdr3_alpha, cdr3_beta, chain_type, v_gene, j_gene.

Example Usage:

query = {
    "name": "iedb_search_tcr_sequences",
    "arguments": {
    }
}
result = tu.run(query)