Gtex Tools

Configuration File: gtex_tools.json Tool Type: Local Tools Count: 2

This page contains all tools defined in the gtex_tools.json configuration file.

Available Tools

GTEx_get_expression_summary (Type: GTExExpressionTool)

Summarize tissue-specific expression (e.g., median TPM) for a gene across GTEx tissues. Accepts g…

GTEx_get_expression_summary tool specification

Tool Information:

  • Name: GTEx_get_expression_summary

  • Type: GTExExpressionTool

  • Description: Summarize tissue-specific expression (e.g., median TPM) for a gene across GTEx tissues. Accepts gene symbols (TP53, BRCA1) or Ensembl IDs. Use to profile baseline expression patterns for targets/biomarkers.

Parameters:

  • gene_symbol (string) (optional) Gene symbol (e.g., ‘TP53’, ‘BRCA1’, ‘FBN1’). Auto-resolved to versioned GENCODE ID.

  • ensembl_gene_id (string) (optional) Ensembl gene identifier (e.g., ‘ENSG00000141510’ or ‘ENSG00000141510.11’). Use gene_symbol instead if you have a gene name.

Example Usage:

query = {
    "name": "GTEx_get_expression_summary",
    "arguments": {
    }
}
result = tu.run(query)

GTEx_query_eqtl (Type: GTExEQTLTool)

Query GTEx single-tissue eQTL associations for a gene. Accepts gene symbols (TP53, BRCA1) or Ense…

GTEx_query_eqtl tool specification

Tool Information:

  • Name: GTEx_query_eqtl

  • Type: GTExEQTLTool

  • Description: Query GTEx single-tissue eQTL associations for a gene. Accepts gene symbols (TP53, BRCA1) or Ensembl IDs. Use to identify regulatory variants (variantId, pValue, slope) relevant to expression regulation.

Parameters:

  • gene_symbol (string) (optional) Gene symbol (e.g., ‘TP53’, ‘BRCA1’). Auto-resolved to versioned GENCODE ID.

  • ensembl_gene_id (string) (optional) Ensembl gene identifier (e.g., ‘ENSG00000141510’). Use gene_symbol instead if you have a gene name.

  • page (integer) (optional) Page number (1-based).

  • size (integer) (optional) Number of records per page (1–100).

Example Usage:

query = {
    "name": "GTEx_query_eqtl",
    "arguments": {
    }
}
result = tu.run(query)