tooluniverse.gnomad_tool module

gnomAD GraphQL API Tool

This tool provides access to the gnomAD (Genome Aggregation Database) for population genetics data, variant frequencies, and gene constraint metrics using GraphQL.

class tooluniverse.gnomad_tool.gnomADGraphQLTool

Bases: BaseTool

Base class for gnomAD GraphQL API tools.

__init__(tool_config)

run(arguments)

Execute GraphQL query with given arguments.

class tooluniverse.gnomad_tool.gnomADGraphQLQueryTool

Bases: gnomADGraphQLTool

Generic gnomAD GraphQL tool driven by JSON config.

Config fields supported: - fields.query_schema: GraphQL query string - fields.variable_map: map tool argument names -> GraphQL variable names - fields.default_variables: default GraphQL variable values

__init__(tool_config)

run(arguments)

Execute GraphQL query with given arguments.

class tooluniverse.gnomad_tool.gnomADGetGeneConstraints

Bases: gnomADGraphQLTool

Get gene constraint metrics from gnomAD.

__init__(tool_config)

run(arguments)

Get gene constraints.