ToolUniverse DocumentationΒΆ

Democratizing AI Scientists for ScienceΒΆ

ToolUniverse is a unified ecosystem that transforms any large language model (LLM)β€”open or closedβ€”into a powerful AI scientist. By standardizing how LLMs identify and call tools, it integrates over 1000 scientific resources, including machine learning models, datasets, APIs, and analysis packages.

With its AI-Tool Interaction Protocol, ToolUniverse provides a common interface for seamless communication between LLMs and tools, ensuring compatibility across platforms such as GPT, Claude, Gemini, and open-source models.

πŸš€ New to ToolUniverse?ΒΆ

Choose your path to get started:

🐍 Writing code?

Choose Python Developer

Use ToolUniverse’s Python API directly in your code, Jupyter notebooks, or custom applications.

Python Guide
πŸ€– Using AI chat?

Choose AI Agent User

Integrate ToolUniverse with Claude, ChatGPT, Gemini, or other AI agents for interactive research.

Choose AI Agent Platform

What Can You Do?ΒΆ

AI Agent Skills - Specialized workflows combining 1000+ scientific tools:

πŸ”¬ Research Skills

Drug discovery, target analysis, disease research, literature reviews, protein design, binder discovery, precision oncology, and more

AI Agent Skills
πŸ› οΈ Development Skills

Create new tools, fix failing tools, optimize descriptions, improve documentation quality, and enhance skill workflows

AI Agent Skills
βš™οΈ Setup & Configuration

Install and configure ToolUniverse with MCP integration for any AI coding client (Cursor, Claude, Gemini, VS Code, etc.)

AI Agent Skills
✨ General Purpose

General strategies for using ToolUniverse effectively: tool discovery, multi-hop queries, comprehensive research workflows

AI Agent Skills

✨ View All Skills: Browse complete catalog with detailed descriptions and usage guides

🌍 Explore More¢

πŸ“– Complete Guide

Comprehensive feature documentation

Tutorial Navigation
πŸ”§ Browse 1000+ Tools

Complete tool catalog with examples

Available Tools
✨ AI Agent Skills

Expert research workflows for AI agents

AI Agent Skills
πŸ”— AI-Tool Protocol

Standardized AI-tool communication

AI-Tool Interaction Protocol
πŸ” Tool Discovery

Find tools by keyword or semantic search

Tool Finder Tutorial
πŸ”— Tool Composition

Chain tools into complex workflows

Tool Composition Tutorial
πŸ“¦ Expand ToolUniverse

Add custom tools and APIs

Navigation
🌐 Deployment Options

Python API, MCP server, HTTP API

MCP Support
πŸ”Œ API Reference

Python API documentation

API Reference
❓ Troubleshooting

Fix common issues

Troubleshooting Tutorial

🌍 Community & Support¢

πŸ› Report Issues

Bug reports and feature requests

https://github.com/mims-harvard/ToolUniverse/issues
🌐 Visit Website

Try tools directly in browser

https://aiscientist.tools

πŸ“š Browse All Documentation - Complete sitemap

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Democratizing AI agents for science with ToolUniverse.